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Year :2017
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Month :
March-April
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Volume :
6
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Issue :
2
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Page :
SC03 - SC05
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Gastric Adenocarcinoma in a Male Patient with Plummer-Vinson Syndrome
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Correspondence Address :
Mathews James, Anandhi Amaranathan, Nishkarsh Mehta, Harshit Kramadhari, Dr. Mathews James,
Plot No 85/86, 1st Cross, 2nd Main Road,
Priyadarshini Nagar, Gorimedu,
Puducherry-605006, India.
E-mail: mathmoola@gmail.com
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Introduction: Plummer-Vinson syndrome (PVS) also known as Paterson- Brown- Kelly syndrome or sideropenic dysphagia has been known for over a century. The syndrome is characterised by a triad of Iron Deficiency Anaemia (IDA), dysphagia and oesophageal webs. It is seen mostly in middle aged women and is considered pre-cancerous condition as 3-15% of the patients develop squamous cell carcinoma involving upper digestive tract mainly oral cavity, tongue, hypopharynx and oesophagus. However, gastric adenocarcinoma has rarely been reported in PVS. We present a case of gastric carcinoma associated with PVS in a 52 years old male patient, presented with history of progressive dysphagia and severe anaemia requiring transfusion. Further, evaluation revealed oesophageal webs and locally advanced antral adenocarcinoma. Literature review has shed light on five similar cases so far.
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