Home
About Us
Issues
Authors
Reviewers
Users
Subscription
Our Other Journals
Site map
Aims and Scope
Salient Features
Editorial Board
Editorial Statements
Editorial-PeerReview Process
Publication Ethics & Malpractice
Ijars Performance
Journal Policy
Contact Us
Current Issue
Forthcoming
Article Archive
Access Statistics
Simple Search
Advanced Search
Submit an Article
Instructions
Assistance
Publication Fee
Paid Services
Apply As Reviewer
Acknowledgment
Register Here Edit Register
Register For Article Submission
Login Here Logout
Login For Article Submission
Annual
Buy One Issue
Payment Options
How to Order
JCDR
IJNMR
NJLM

 

Welcome : Guest

Users Online :

 

 

 

 

 

 

 

 

Original article / research

Year :2020 Month : September-October Volume : 9 Issue : 4 Page : RO12 - RO15

Diagnostic Accuracy of Thyroid Imaging, Reporting and Data System Combined with Strain Elastography in the Evaluation of Thyroid Nodules

Correspondence Address :
Priyanka Kalaiarasan, Senthil Kumar Aiyappan, Vinayagam Shanmugam, Parminder Singh Purewal,
Senthil Kumar Aiyappan,
Department of radiology, SRM Medical College Hospital and Research Centre, Kattankulathur, Chengalpattu, Tamil Nadu-603203, India.
E-mail: asenthilkumarpgi@gmail.com
Introduction: Introduction: It is estimated that the prevalence of thyroid nodules is about 3-8% and there are always chances of malignancy in thyroid nodule which should not be underestimated. Fine Needle Aspiration Cytology (FNAC) is an efficient tool for diagnosing thyroid malignancies. Strain elastography measures the stiffness of nodules using ultrasound and serves as an additional diagnostic tool in differentiating benign and malignant thyroid nodules depending on their hardness.

Aim: To characterise thyroid nodules based on Thyroid Imaging Reporting And Data System (TIRADS) combined with strain elastography in differentiating benign from malignant thyroid nodules and correlating them with FNAC/Histopathological Examination (HPE).

Materials and Methods: A prospective cross-sectional study was conducted in which total of 135 patients were included who were diagnosed to have thyroid nodules by B-mode ultrasound or by palpation. For the evaluation of the strain ratio, the average strain value was obtained from 4 continuous frames of strain images and ratio of less than 2.50 was benign and more than 2.50 was considered malignant. Combined TIRADS and strain elastography scores were obtained and the results were correlated with histological findings by performing an FNAC/Biopsy. All statistical analysis were performed using Statistical Package for Social Science (SPSS, version 17) for Microsoft windows. The data were expressed as Mean and Standard Deviation (SD). Chi- square test were used for qualitative data.

Results: Among the 135 thyroid nodules, Ultrasonography (USG) TIRADS scoring system differentiated benign and malignant nodules with sensitivity of 83%, while the specificity was 96.4%, Positive Predictive Value (PPV)=83.3%, Negative Predictive Value (NPV)=96.4% and accuracy of 94.1%. Strain elastography differentiated benign from malignant nodules with of sensitivity was 91.7%, while the specificity was 99.0%, PPV=95.7%, NPV=95.7% and accuracy of 98% while the combined TIRADS and strain elastography score differentiated benign from malignant nodules with sensitivity of 95.83%, while the specificity was 100%, PPV=100%, NPV=99.1% and accuracy of 99.3%.

Conclusion: Grey scale ultrasound is an efficient tool for diagnosis of thyroid nodules. Elastography can further help in characterising thyroid nodules and can help in identifying sites for FNAC. Combination of both B-mode Ultrasound findings and strain elastography yield a better diagnosis.
 
[ FULL TEXT ]   |   [ ]
 

Article Utilities

  • Readers Comments
  • Article in PDF
  • Citation Manager
  • Article Statistics
  • Link to PUBMED
  • Print this Article
  • Send to a Friend

Quick Links

REVIEWER
ACCESS STATISTICS
Home  |  About Us  |  Online First  |  Current Issue  |  Simple Search  |  Advance Search  |  Register  |  Login  |  Contact  |  Privacy Policy  |  Terms of Use
Author Support  |  Submit Manuscript  |  IJARS Pre-Publishing  |  Reviewer  |  Articles Archive  |  Access Statistics
©INTERNATIONAL JOURNAL OF ANATOMY RADIOLOGY & SURGERY (IJARS), ISSN : 2277-8543.
EDITORIAL OFFICE : 1/9, Roop Nagar, Delhi 11000. Phone : 01123848553

* This Journal is owned and run by medical professionals *