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Year :2021
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Month :
January-February
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Volume :
10
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Issue :
1
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Page :
SO05 - SO08
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Effect of Preoperative Hypovitaminosis D
on Post-Total Thyroidectomy Transient
Hypocalcaemia: A Retrospective
Cross-sectional Study
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Correspondence Address :
Bhavuray Teli, R Santhosh, MP Udayaravi, PP Dinesh, Satish Arkeri, N Naveen, Ganesan Karthick, PR Venugopal,
Dr. PP Dinesh,
Assistant Professor, Department of Surgery, Malabar Medical College, Kozhikode -673323, Kerala, India.
E-mail: ppd.mmch@gmail.com;drsanthoshr@ymail.com
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Introduction: Introduction: Total Thyroidectomy (TT) is a standard surgical procedure for Multinodular Goiter (MNG). Transient hypocalcaemia is a frequent complication of TT with significant postoperative morbidity and long-term consequences. Many patient and surgical factors are attributed to postoperative hypocalcaemia. Vitamin D deficiency is one of the contributory factors in few of the studies, which is a modifiable risk factor. However, there is limited data to support the same.
Aim: To evaluate the effect of preoperative vitamin D deficiency on postoperative hypocalcaemia in patients undergoing TT surgery.
Materials and Methods: This was a retrospective cross-sectional, descriptive study done on patients undergoing TT for MNG in a single general surgical unit at a tertiary care teaching hospital in Southern India. The data pertaining to patients undergoing TT for MNG between January 2017 to February 2018 were collected. Patients who had low preoperative vitamin D levels before surgery were included. The preoperative vitamin D levels were correlated with postsurgery total serum calcium using pearson correlation and the association of preoperative serum total calcium was examined with postoperative serum total calcium by using paired t-test. The results were analysed using Statistical Package for the Social Sciences (SPSS) Version 20. The p-value<0.05 was considered statistically significant.
Results: Thirty-two patients had preoperative documented vitamin D deficiency. Preoperative mean serum vitamin D level was 15.42 ng/mL (R=3.21 to 29 ng/mL). Mean preoperative calcium level was 9.28±0.51 mg/dL at admission. Postoperatively mean serum total calcium level was 8.54±0.47 mg/dL. There was no correlation between preoperative vitamin D levels and postoperative low serum calcium levels (Pearson R=0.154).
Conclusion: There was no influence of preoperative vitamin D levels on postoperative transient hypocalcaemia. Prospective studies with well-defined controls in a larger cohort are needed for ascertaining the same, as it has wider clinical implications.
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