Home
About Us
Issues
Authors
Reviewers
Users
Subscription
Our Other Journals
Site map
Aims and Scope
Salient Features
Editorial Board
Editorial Statements
Editorial-PeerReview Process
Publication Ethics & Malpractice
Ijars Performance
Journal Policy
Contact Us
Current Issue
Forthcoming
Article Archive
Access Statistics
Simple Search
Advanced Search
Submit an Article
Instructions
Assistance
Publication Fee
Paid Services
Apply As Reviewer
Acknowledgment
Register Here Edit Register
Register For Article Submission
Login Here Logout
Login For Article Submission
Annual
Buy One Issue
Payment Options
How to Order
JCDR
IJNMR
NJLM

 

Welcome : Guest

Users Online :

 

 

 

 

 

 

 

 

Original article / research

2021
Year :2021 Month : July-August Volume : 10 Issue : 3 Page : RO21 - RO24

Diffusion Weighted Imaging on a 3 Tesla Magnetic Resonance Scanner as a Diagnostic Tool in Early Detection of Prostate Cancer

Published: July 1, 2021 | DOI: https://doi.org/10.7860/JCDR/2021/48949.2668
Correspondence Address :
Ruchira Das, Archana Singh, Sudipta Saha, Shubham Saha, Dilip Kumar Pal, Utpalendu Das, Madan Karmakar,
Archana Singh,
Associate Professor, Department of Radiodiagnosis, IPGME&R and SSKM Hospital, 244, AJC Bose Road, Kolkata, West Bengal, India.
E-mail: asinghrd@gmail.com
Introduction: Introduction: Multiparametric Magnetic Resonance Imaging (MRI) of prostate including Diffusion Weighted Imaging (DWI) is greatly evolving as a diagnostic tool in prostate cancer. Incidence of prostate cancer in India is on rise with most of the cases been diagnosed in late stages. In this scenario, DWI imaging can pick up the cases at an earlier stage causing a significant impact in the patient management.

Aim: To assess the role of DW-MRI as a non invasive initial investigation tool in prostate carcinoma prior to biopsy.

Materials and Methods: The study was a prospective observational study conducted during April 2014 to March 2015 in the Department of Radiodiagnosis in collaboration with Department of Urology in a hospital in Kolkata. A total of 34 patients with a clinical suspicion of prostate cancer underwent prostate DWI-MRI by a 3T scanner before Transrectal Ultrasound (TRUS)-guided biopsies. IBM Statistical Package for Social sciences (SPSS) version 17.0 was used for statistical analysis and the sensitivity, specificity, Positive Predictive Value (PPV) and Negative Predictive Value (NPV) were determined.

Results: All patients (100%) with biopsy proven adenocarcinoma showed diffusion restriction. A total of 95.8% were PI-RADS 5. False positive results were found in two patients. The sensitivity, specificity, PPV and NPV were 100% (95% CI=85.75% to 100.00%), 80% (95% CI=44.39% to 97.48%), 92.31% (95% CI=74.87% to 99.05%) and 100% (95% CI=63.06% to 100.00%)

Conclusion: From the present study, it was noted that sensitivity of DWI is very high (100%). DWI also has a high specificity and positive predictive value. Hence, DWI is one of the most effective adjunct non invasive tools for initial investigation in prostate carcinoma which improves the diagnostic performance and helps in performing targeted biopsies from the suspicious prostatic lesion.
 
[ FULL TEXT ]   |   [ ]
 

Article Utilities

  • Readers Comments
  • Article in PDF
  • Citation Manager
  • Article Statistics
  • Link to PUBMED
  • Print this Article
  • Send to a Friend

Quick Links

REVIEWER
ACCESS STATISTICS
Home  |  About Us  |  Online First  |  Current Issue  |  Simple Search  |  Advance Search  |  Register  |  Login  |  Contact  |  Privacy Policy  |  Terms of Use
Author Support  |  Submit Manuscript  |  IJARS Pre-Publishing  |  Reviewer  |  Articles Archive  |  Access Statistics
©INTERNATIONAL JOURNAL OF ANATOMY RADIOLOGY & SURGERY (IJARS), ISSN : 2277-8543.
EDITORIAL OFFICE : 1/9, Roop Nagar, Delhi 11000. Phone : 01123848553

* This Journal is owned and run by medical professionals *