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Year :2021
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Month :
September-October
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Volume :
10
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Issue :
4
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Page :
RO25 - RO29
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Radiological Findings of Thoracic Sarcoidosis in an Indian Cohort: A Retrospective Study
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Correspondence Address :
Tharani Putta, Aparna Irodi, RV Leena, Binita Riya Chacko, Devasahayam Christopher,
Dr. Tharani Putta,
Associate Professor, Department of Radiology, Christian Medical College,
Vellore-632004, Tamil Nadu, India.
E-mail: tharaniputta@gmail.com
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Introduction: Introduction: Sarcoidosis is commonly mistaken for tuberculosis in India. Imaging is of paramount importance in making a correct diagnosis, but, most of the published literature available on radiological findings of sarcoidosis is from the Western population.
Aim: To study the radiological findings of thoracic sarcoidosis in Indian patients.
Materials and Methods: This was a retrospective descriptive study done in a tertiary hospital in Southern India after obtaining clearance from Institutional Review board and Ethics Committee (IRB Min no 6997). Ninety-six patients diagnosed with sarcoidosis between January 2001 and August 2009 based on a combination of clinical, radiological and histopathological findings were included in the study. Their chest radiographs and High-Resolution Computerised Tomography (HRCT) thorax at presentation were reviewed and radiological findings were documented on a proforma. Statistical Package for the Social Sciences (SPSS, IBM Corp., Armonk, NY) software version 21.0 was used for statistical analysis.
Results: The HRCT was abnormal in all the study patients with lymphadenopathy seen in 87 patients (90.6%) and lung parenchymal abnormality in 92 patients (95.8%). Mediastinal nodes were more commonly seen when compared with hilar lymphadenopathy. The typical lung parenchymal findings seen were juxta-fissural or subpleural nodules and peribronchovascular nodular interstitial thickening. Late irreversible findings were seen at least focally in 43 patients (45%). The classically described upper zone lung predilection was not seen in this study.
Conclusion: Paratracheal and subcarinal lymphadenopathy are more common than hilar lymphadenopathy in sarcoidosis. Despite overlapping radiological findings between pulmonary sarcoidosis and tuberculosis, the presence of hyperdense nodes, fissural nodularity, peribronchovascular nodular interstitial thickening with perihilar prominence of findings should favour diagnosis of sarcoidosis.
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