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Original article / research

2022
Year :2022 Month : January-February Volume : 11 Issue : 1 Page : RO18 - RO21

Evaluation of Effect of Fatty Liver on the Severity of Acute Pancreatitis Using Computed Tomography- A Retrospective Study

Published: January 1, 2022 | DOI: https://doi.org/10.7860/JCDR/2022/51279.2730
Correspondence Address :
Venkat Kishan Tatikonda, Sindhura Indurti,
Venkat Kishan Tatikonda,
1-2-234/25, Plot No: 12g SBH Colony Domalguda Hyderabad, Hyderabad,
Telangana, India.
E-mail: venkatkishanresearch@gmail.com
Introduction: Introduction: Fatty Liver (FL) disease is commonly encountered in clinical practice and is frequently seen in patients with Acute Pancreatitis (AP) due to common risk factors such as obesity, alcohol abuse, and insulin resistance among others.

Aim: To evaluate the effect of FL on the severity of AP radiologically using Computed Tomography (CT).

Materials and Methods: This was a retrospective study, conducted from June 2021 to July 2021 in which plain CT images of patients with AP were reviewed to measure the mean attenuation values of the liver and spleen. A ratio of mean hepatic/splenic Hounsfield Units (HU) <1 was considered as FL. The severity of AP was assessed using the Modified CT Severity Index (CTSI) on Contrast Enhanced Computed Tomography (CECT) scan. Data collected was entered into Microsoft Excel datasheet and frequency (n) and percentages were calculated. Chi-square test was used to calculate the level of significance.

Results: A total of 50 patients (44 males and 6 females; mean age 35.58±13.792 years) with AP were included in this study amongst whom FL was found in 23 patients (46%) and non FL in 27 patients (54%). The severity of pancreatitis was significantly greater in patients with FL than patients without FL. AP patients with FL had higher rates of local complications like acute Peripancreatic Fluid Collections (PPFC) (56.5% vs 22.2% p<0.001) and Acute Necrotic Collections (ANC) (26.1% vs 3.7% p<0.001) than those without FL.

Conclusion: Fatty liver plays a significant role in the severity acute pancreatitis and can be used as an indicator for the same. Combined plain and contrast CT scans can be used to assess FL and diagnose and predict the severity of AP.
 
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