Home
About Us
Issues
Authors
Reviewers
Users
Subscription
Our Other Journals
Site map
Aims and Scope
Salient Features
Editorial Board
Editorial Statements
Editorial-PeerReview Process
Publication Ethics & Malpractice
Ijars Performance
Journal Policy
Contact Us
Current Issue
Forthcoming
Article Archive
Access Statistics
Simple Search
Advanced Search
Submit an Article
Instructions
Assistance
Publication Fee
Paid Services
Apply As Reviewer
Acknowledgment
Register Here Edit Register
Register For Article Submission
Login Here Logout
Login For Article Submission
Annual
Buy One Issue
Payment Options
How to Order
JCDR
IJNMR
NJLM

 

Welcome : Guest

Users Online :

 

 

 

 

 

 

 

 

Original article / research

2022
Year :2022 Month : September-October Volume : 11 Issue : 4 Page : AO19 - AO23

Comparative Cytomorphometric Study of Exfoliated Squamous Buccal Cells among Patients with Iron Deficiency Anaemia and Healthy Individuals in Saurashtra, Gujarat, India

Published: October 1, 2022 | DOI: https://doi.org/10.7860/JCDR/2022/55633.2829
Correspondence Address :
Ritika M Patel, Ridhdhish K Patel,
Ritika M Patel,
Assistant Professor, Department of Anatomy, Dr. Kiran C Patel, Medical College and Research Institute, Civil Hospital, Bharuch, Gujarat, India.
E-mail: doc.ritika@yahoo.in
Introduction: Introduction: Cytology is a fast, simple, non invasive, and bloodless procedure. Cytology can be useful in cases where biopsy is contraindicated or not needed, such as in systemically compromised patients, inaccessible areas, recurrent malignancies and mass screening. The most common nutritional disorder in the world is iron deficiency and it is more prevalent in India. Exfoliative cytology is becoming increasingly recognised as a standard technique for screening oral pathologies like anaemia.

Aim: To compare the Nucleus Diameters (ND), the Cytoplasmic Diameters (CD), and the Nucleus/Cytoplasmic ratio (N/C) in cytological buccal smears of iron deficiency anaemic patients and with normal healthy individuals.

Materials and Methods: The case-control study was conducted in Department of Anatomy, G.G hospital connected MP Shah Government Medical College, Jamnagar, Gujarat, India, from August 2013 to February 2016, which included 50 healthy individuals and 50 clinically diagnosed patients of iron deficiency anaemia. Exfoliated buccal smears stained with routine Haematoxylin and Eosin (H&E) staining technique. With the use of ocular micrometer, CD, ND and N/C ratio were calculated. All the parameters were statistically evaluated by using Student t-test.

Results: The mean value of nuclear diameter 11.34±0.58 μm and N/C ratio (0.24±0.02) of buccal mucosa was greater while cytoplasmic diameter 46.57±2.03 μm was lesser in iron deficiency anaemia when compared with healthy individuals. A significant difference was not found when comparing different age groups, as well as male versus female cases and male versus female controls. Comparing cases and controls by gender, however produced significant statistical results.

Conclusion: Statistically significant difference was found between iron deficiency anaemia patients and normal healthy individuals regarding changes in various parameters of buccal squamous cells. In the case of iron deficiency anaemia, oral exfoliative cytological techniques could be used as an alternative non invasive diagnostic tool.
 
[ FULL TEXT ]   |   [ ]
 

Article Utilities

  • Readers Comments
  • Article in PDF
  • Citation Manager
  • Article Statistics
  • Link to PUBMED
  • Print this Article
  • Send to a Friend

Quick Links

REVIEWER
ACCESS STATISTICS
Home  |  About Us  |  Online First  |  Current Issue  |  Simple Search  |  Advance Search  |  Register  |  Login  |  Contact  |  Privacy Policy  |  Terms of Use
Author Support  |  Submit Manuscript  |  IJARS Pre-Publishing  |  Reviewer  |  Articles Archive  |  Access Statistics
©INTERNATIONAL JOURNAL OF ANATOMY RADIOLOGY & SURGERY (IJARS), ISSN : 2277-8543.
EDITORIAL OFFICE : 1/9, Roop Nagar, Delhi 11000. Phone : 01123848553

* This Journal is owned and run by medical professionals *