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Year :2024
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Month :
November-December
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Volume :
13
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Issue :
6
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Page :
SO09 - SO13
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Clinical and Bacteriological Profile of Necrotising Fasciitis at a Tertiary Care Hospital, New Delhi: An Observational Study
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Correspondence Address :
VR Karthikayan, Arun Gupta, NG Pradeep Kumar,
NG Pradeep Kumar,
Nelamangala, Bengaluru Rural-562123, Bengaluru, Karnataka, India.
E-mail: pradeepbmcripsm2020@gmail.com
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Introduction: Introduction: Necrotising Soft Tissue Infection (NSTI) is a rapidly progressing infection characterised by extensive necrosis and widespread destruction of the soft tissues located anywhere from the superficial epidermis of the skin to the deep musculature.
Aim: To explore the clinical characteristics and identify the bacterial agents responsible for Necrotising Fasciitis (NF).
Materials and Methods: The present observational study was conducted in the Department of Surgery, University College of Medical Sciences and Guru Teg Bahadur (GTB) Hospital, New Delhi, India, from November 2017 to April 2019, involving 77 NF patients. The clinical characteristics and identification of bacterial agents were achieved by analysing clinical specimens from cases clinically diagnosed with NF. The antibiotic resistance patterns of these bacterial isolates were also determined. Data was recorded in an Excel worksheet, and statistical analysis was conducted using Statistical Package for Social Sciences (SPSS) software version 21.0.
Results: Total of 77 patients were included, among which 62 (80.5%) were males and 15 (19.4%) were females with the mean±Standard Deviation (SD) age 43.96±19.3 years. The most common bacteria isolated were Escherichia coli, 20 (25.3%). Staphylococcus aureus was isolated in nine patients, and of them, six were Methicillin-resistant Staphylococcus Aureus (MRSA).
Conclusion: Early detection of NF, a severe infectious condition, can significantly reduce morbidity and mortality. The findings underscore the critical need for early diagnosis and treatment due to significant mortality rates.
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