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Surgical Site Infections in Single-dose versus Multiple-dose Broad-spectrum Intravenous Antibiotic Prophylaxis in Clean Surgeries: A Quasi-experimental Study |
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C Shobha, Amit Kumar, Bhimanagouda V Goudar, Shaileshkumar M Emmi 1. Assistant Professor, Department of General Surgery, Nijalingappa Medical College and Kumareshwara Hospital, Bagalkot, Karnataka, India. 2. Senior Resident, Department of General Surgery, Nijalingappa Medical College and Kumareshwara Hospital, Bagalkot, Karnataka, India. 3. Professor, Department of General Surgery, Nijalingappa Medical College and Kumareshwara Hospital, Bagalkot, Karnataka, India. 4. Professor, Department of General Surgery, Nijalingappa Medical College and Kumareshwara Hospital, Bagalkot, Karnataka, India. |
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Correspondence Address : Dr. C Shobha, MCh Doctors New Quarters, Navnagar, Government District Hospital, Navnagar, Bagalkot-587103, Karnataka, India. E-mail: drshobhacnaik@gmail.com |
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| ABSTRACT |  | ||||||
: Introduction: Surgical Site Infections (SSIs) constitute a prevalent nosocomial concern among surgical patients. The incidence of SSIs typically ranges from 1-2% in the context of clean surgeries, irrespective of the use of antibiotic prophylaxis. Frequently, a single preoperative dose of antibiotics administered up to 60 minutes before surgery suffices. Aim: To compare the rates of postoperative infections following a single preoperative dose of prophylactic antibiotics with those receiving multiple postoperative doses. Materials and Methods: This quasi-experimental study was conducted at the Surgery Department of Kumareshwara Hospital in Bagalkot, Karnataka, India. Participants included individuals aged over 18 years undergoing elective clean surgeries, with their informed consent. Patients with co-morbidities or pre-existing infections at the surgical site were excluded from the study. A total of 161 cases were enrolled, divided into two groups: Group A (single dose of broad-spectrum i.v. antibiotic with 70 patients) and Group B (multiple doses of the same broad-spectrum antibiotic with 91 patients). Independent parameters of outcome variables were analysed using the Chi-square test and Student’s t-test. Results: The mean age of study participants was 41.25±13.47 years. The incidence of SSI in Group A was 1.42%, while in Group B, it was 2.20%. The mean duration of hospital stay was shorter in Group A (6.11±3.87 days) compared to Group B (7.60±4.08 days). Conclusion: In conclusion, the study suggests that the incidence of SSIs in both groups is similar and statistically insignificant for clean surgeries. Importantly, the hospital stay was shorter in the group receiving a single preoperative dose of antibiotics compared to multiple doses of antibiotics. | |||||||
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| Keywords : Chemoprophylaxis, Hernioplasty, Hospital stay, Nosocomial infection, Spectrum antibiotic | |||||||
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DOI and Others :
DOI: 10.7860/IJARS/2024/69439.2987
Date of Submission: Jan 05, 2024 Date of Peer Review: Feb 17, 2024 Date of Acceptance: Apr 04, 2024 Date of Publishing: May 01, 2024 AUTHOR DECLARATION: • Financial or Other Competing Interests: None • Was Ethics Committee Approval obtained for this study? Yes • Was informed consent obtained from the subjects involved in the study? Yes • For any images presented appropriate consent has been obtained from the subjects. Yes PLAGIARISM CHECKING MET |
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